Canada’s Carney says rate hikes “less imminent”
















TORONTO (Reuters) – Interest rate hikes have become less imminent than the Bank of Canada once expected, although rates are still likely to rise, central bank Governor Mark Carney said in an interview published on Saturday.


“Over time, rates are likely to increase somewhat, but over time, so a less imminent timing relative to our expectation,” Carney said in an interview with the National Post newspaper.













Canada’s economy rebounded better than most from the global economic recession, and the Bank of Canada is the only central bank in the Group of Seven leading industrialized nations that is currently hinting at higher interest rates.


But Carney has also made clear that there will be no rate rise for a while, despite high domestic borrowing rates that he sees as a major risk to a still fragile economy.


“We’ve been very clear in terms of lines of defense in addressing financial vulnerabilities,” he said in the interview. “And the most prominent one, obviously, in Canada, is household debt.”


He said the bank was monitoring the impact of four successive government moves to tighten mortgage lending, which aimed to take the froth out of a hot housing market without causing a damaging crash in prices.


A Reuters poll published on Friday showed the majority of 20 forecasters believe the government has done enough to rein in runaway prices, preventing the type of crash that devastated the U.S. market.


The experts expect Canadian housing prices to fall 10 percent over the next several years, but they do not expect the recent property boom to end in a U.S.-style collapse.


(Reporting by Janet Guttsman; Editing by Vicki Allen)


Canada News Headlines – Yahoo! News



Read More..

With TV and film production heading overseas, should Uncle Sam get into showbiz?
















LOS ANGELES (TheWrap.com) – Is it time for Uncle Sam to go Hollywood?


With the exodus of film and TV production to foreign shores – and with the states’ incentives plans frequently out-gunned by countries outside the U.S. – there is some thought that it may be time for the federal government to step in.













The idea of the federal government helping out Hollywood while it is drowning in red ink is sure to raise hackles in some quarters. But filmmaker Michael Moore, for one, thinks it’s an idea whose time has come. And he’s not alone.


“That is one good thing the government can do in terms of being helpful and supportive, whether it’s filmmaking or other artistic endeavors,” Moore told TheWrap.


And he added, it’s also time for the states to stop fighting each other with differing tax-incentive plans. “I’ve always opposed New Mexico against North Carolina, or Michigan against L.A. I don’t like that. It’s not right. We’re Americans.”


Moore is not alone.


There are reasons to keep TV and film production from going abroad. The industry provides more than 2.4 million American jobs and adds nearly $ 180 billion to the U.S. economy annually and $ 15 billion in federal and state taxes, according to the Motion Picture Association of America.


Joe Chianese, executive VP at showbiz payroll giant Entertainment Partners Financial Solutions, believes the idea of getting the feds involved makes sense.


“You watched the debates and heard both President Obama and Gov. Romney talking about how it’s all about jobs, and they talked about how the manufacturing industry has basically been lost to overseas,” Chianese told TheWrap. “Well, we’re looking at the same sort of situation with the TV and film industry if something isn’t done.”


As he spoke to TheWrap, Chianese was about to set off for Japan, where government and film-industry officials were considering an incentive program that would align them with the more than 30 foreign countries trying to lure U.S. entertainment productions.


“You can’t blame filmmakers for taking their business elsewhere,” he said. “They’re taking their work overseas for the same reasons manufacturers are: It’s cheaper.”


Until recently, the federal government provided some help. Section 181 of the current tax code lowered the cost of capital for domestic film and TV production by providing immediate expensing on the first $ 15 million of production costs. To be eligible, 75 percent of the production had to occur in the U.S.


But it expired at the end of 2011.


California Republican Congressmen David Dreier has co-authored legislation to bring 181 back for another two years, but it is mired in Congress, along with a number of other tax-law extensions.


“Jobs are our No. 1 priority, and this bill will help more people find good jobs in California and across the U.S.,” said Dreier, who represents much of the San Gabriel Valley. “We need to create an environment that will keep entertainment productions here so that caterers, makeup artists and other small businesses that support them can create jobs too.”


Amy Lemistch, executive director of the California Film Commission, shares the world view on keeping show business here.


“We see California’s runaway production problem as a global issue,” she told TheWrap “not a state vs. state issue. People are going to the U.K. and Canada as much as they are going to other states.”


Smaller nations like Sri Lanka have begun offering breaks, and others like New Zealand have ramped up state-of-the-art production infrastructures. Even Iceland recently lured the HBO series “Game of Thrones” and the feature films “Noah” and “Prometheus.”


Particularly galling to California Film Commission officials is when productions set in the state are lured overseas. Recent examples would be the now-canceled Fox TV series “Alcratraz” and the L.A.-set movie “This Means War,” both of which shot in Vancouver.


Unlike Moore, Chianese, a tax specialist who worked with the commission when it was crafting its credits program, sees the federal incentives coming on top of state credits, rather than replacing them.


“You add, say, a 15 percent jobs credit, where companies would get 15 percent of the salary of every hire they make,” he said. “Add that on top of, say, the 25 percent credit California offers, and you’re up to 40 percent credit. That would make a real difference when it comes to keeping entertainment jobs here.”


Chianese said he’d be willing to see Section 181 go away in favor of more direct and immediate incentives. But with Obama and Congress focused on cutbacks and new taxes to pare down the national debt before the end of the year, the timing’s not good now.


It will always be an uphill fight, particularly with the House of Representatives controlled by the budget-conscious GOP.


“You’d face the same question you always do with incentives, which is: Why favor one industry over another?” Chianese said.


Not to mention major blowback from the segments of the right, which see liberal politicians as too tied to Hollywood already.


As for state credits, Hollywood breathed a sigh of relief in late September when California Gov. Jerry Brown signed a two-year extension of the state’s film and TV production-tax credit program. But no one expects it to be a game-changer when it comes to California’s fight to remain the world’s production capital.


New York, for example, is offering 30 percent tax credits, has $ 420 million available and recently added a 25 to 30 percent credit for post-production work. By comparison, California offers a 25 percent credit, has just $ 100 million available and has tougher eligibility rules.


Still, Lemisch said, the extension was critical.


“It sends a signal to the production community that California is committed in the short and long term,” she said. That’s vital, she pointed out, especially for the producers of TV dramas, which are the most desirable shows to land because they’re typically an hour long and shoot multiple episodes.


California’s output of TV dramas fell more than 11 percent last year, while While New York was hitting record production levels.


California does have some built-in advantages that aren’t going away. If you’re based in Hollywood, staying here can be cheaper than going out of state even with incentives, because you’re not paying to ship equipment and transport crews. The state’s infrastructure of studios and post-production facilities is still the most extensive.


But that doesn’t mean other states aren’t beating California to the production punch.


North Carolina – which made headlines when it enticed the feature film “Battlefield Los Angeles” to shoot there instead of in L.A. – is very busy these days. The first “Hunger Games” was filmed there, as was “Iron Man 3.’ NBC’s new drama “Revolution” and Showtime’s “Homeland” are in production there now.


Georgia, too, has seen a recent surge in feature filming. Paramount’s “Flight,” Fox’s “Parental Guidance” and Warner Bros.’ “Trouble With the Curve” all shot there.


(Steve Pond contributed to this report)


TV News Headlines – Yahoo! News



Read More..

With TV and film production heading overseas, should Uncle Sam get into showbiz?
















LOS ANGELES (TheWrap.com) – Is it time for Uncle Sam to go Hollywood?


With the exodus of film and TV production to foreign shores – and with the states’ incentives plans frequently out-gunned by countries outside the U.S. – there is some thought that it may be time for the federal government to step in.













The idea of the federal government helping out Hollywood while it is drowning in red ink is sure to raise hackles in some quarters. But filmmaker Michael Moore, for one, thinks it’s an idea whose time has come. And he’s not alone.


“That is one good thing the government can do in terms of being helpful and supportive, whether it’s filmmaking or other artistic endeavors,” Moore told TheWrap.


And he added, it’s also time for the states to stop fighting each other with differing tax-incentive plans. “I’ve always opposed New Mexico against North Carolina, or Michigan against L.A. I don’t like that. It’s not right. We’re Americans.”


Moore is not alone.


There are reasons to keep TV and film production from going abroad. The industry provides more than 2.4 million American jobs and adds nearly $ 180 billion to the U.S. economy annually and $ 15 billion in federal and state taxes, according to the Motion Picture Association of America.


Joe Chianese, executive VP at showbiz payroll giant Entertainment Partners Financial Solutions, believes the idea of getting the feds involved makes sense.


“You watched the debates and heard both President Obama and Gov. Romney talking about how it’s all about jobs, and they talked about how the manufacturing industry has basically been lost to overseas,” Chianese told TheWrap. “Well, we’re looking at the same sort of situation with the TV and film industry if something isn’t done.”


As he spoke to TheWrap, Chianese was about to set off for Japan, where government and film-industry officials were considering an incentive program that would align them with the more than 30 foreign countries trying to lure U.S. entertainment productions.


“You can’t blame filmmakers for taking their business elsewhere,” he said. “They’re taking their work overseas for the same reasons manufacturers are: It’s cheaper.”


Until recently, the federal government provided some help. Section 181 of the current tax code lowered the cost of capital for domestic film and TV production by providing immediate expensing on the first $ 15 million of production costs. To be eligible, 75 percent of the production had to occur in the U.S.


But it expired at the end of 2011.


California Republican Congressmen David Dreier has co-authored legislation to bring 181 back for another two years, but it is mired in Congress, along with a number of other tax-law extensions.


“Jobs are our No. 1 priority, and this bill will help more people find good jobs in California and across the U.S.,” said Dreier, who represents much of the San Gabriel Valley. “We need to create an environment that will keep entertainment productions here so that caterers, makeup artists and other small businesses that support them can create jobs too.”


Amy Lemistch, executive director of the California Film Commission, shares the world view on keeping show business here.


“We see California’s runaway production problem as a global issue,” she told TheWrap “not a state vs. state issue. People are going to the U.K. and Canada as much as they are going to other states.”


Smaller nations like Sri Lanka have begun offering breaks, and others like New Zealand have ramped up state-of-the-art production infrastructures. Even Iceland recently lured the HBO series “Game of Thrones” and the feature films “Noah” and “Prometheus.”


Particularly galling to California Film Commission officials is when productions set in the state are lured overseas. Recent examples would be the now-canceled Fox TV series “Alcratraz” and the L.A.-set movie “This Means War,” both of which shot in Vancouver.


Unlike Moore, Chianese, a tax specialist who worked with the commission when it was crafting its credits program, sees the federal incentives coming on top of state credits, rather than replacing them.


“You add, say, a 15 percent jobs credit, where companies would get 15 percent of the salary of every hire they make,” he said. “Add that on top of, say, the 25 percent credit California offers, and you’re up to 40 percent credit. That would make a real difference when it comes to keeping entertainment jobs here.”


Chianese said he’d be willing to see Section 181 go away in favor of more direct and immediate incentives. But with Obama and Congress focused on cutbacks and new taxes to pare down the national debt before the end of the year, the timing’s not good now.


It will always be an uphill fight, particularly with the House of Representatives controlled by the budget-conscious GOP.


“You’d face the same question you always do with incentives, which is: Why favor one industry over another?” Chianese said.


Not to mention major blowback from the segments of the right, which see liberal politicians as too tied to Hollywood already.


As for state credits, Hollywood breathed a sigh of relief in late September when California Gov. Jerry Brown signed a two-year extension of the state’s film and TV production-tax credit program. But no one expects it to be a game-changer when it comes to California’s fight to remain the world’s production capital.


New York, for example, is offering 30 percent tax credits, has $ 420 million available and recently added a 25 to 30 percent credit for post-production work. By comparison, California offers a 25 percent credit, has just $ 100 million available and has tougher eligibility rules.


Still, Lemisch said, the extension was critical.


“It sends a signal to the production community that California is committed in the short and long term,” she said. That’s vital, she pointed out, especially for the producers of TV dramas, which are the most desirable shows to land because they’re typically an hour long and shoot multiple episodes.


California’s output of TV dramas fell more than 11 percent last year, while While New York was hitting record production levels.


California does have some built-in advantages that aren’t going away. If you’re based in Hollywood, staying here can be cheaper than going out of state even with incentives, because you’re not paying to ship equipment and transport crews. The state’s infrastructure of studios and post-production facilities is still the most extensive.


But that doesn’t mean other states aren’t beating California to the production punch.


North Carolina – which made headlines when it enticed the feature film “Battlefield Los Angeles” to shoot there instead of in L.A. – is very busy these days. The first “Hunger Games” was filmed there, as was “Iron Man 3.’ NBC’s new drama “Revolution” and Showtime’s “Homeland” are in production there now.


Georgia, too, has seen a recent surge in feature filming. Paramount’s “Flight,” Fox’s “Parental Guidance” and Warner Bros.’ “Trouble With the Curve” all shot there.


(Steve Pond contributed to this report)


TV News Headlines – Yahoo! News



Read More..

Beating tax cheats key to Italy’s recovery plan
















ROME (AP) — Good plumbers may be worth their weight in gold, but when one was spotted zipping around in a bright red Ferrari, Italian tax police were fast on his trail.


Stamping out entrenched tax evasion is crucial to Premier Mario Monti‘s quest to keep Italy from succumbing to the European debt crisis, and it is critical to fellow eurozone members in more dire straits, such as Greece and Spain — which are also notorious for making cheating the taxman a way of life.













Indeed, Greece’s international rescue creditors have been pressing Greece for two years to reform its ailing tax system, citing poor collection as a key factor keeping the country mired in crisis. In Spain, where tax fraud is rampant, as much as €90 billion ($ 150 billion) is lost each year to tax fraud — the equivalent of the country’s national debt, according to Spain’s main tax inspectors union.


To succeed in Italy, authorities will have to catch the legions of self-employed and small business owners who brazenly lie about their earnings, like the plumber in the eastern town of Pescara, who socked away undeclared income in 30 bank accounts, or a successful pastry shop owner in Calabria, who on his tax return claimed he was earning next to crumbs.


And those are the less sophisticated schemers.


Tax police officials say that wealthy Italians, their companies and foreigners who make their money in Italy are increasingly trying to avoid taxes by using such strategies as falsely declaring that their base of operations or residence is abroad.


Another daunting challenge is the so-called “submerged” economy, a term embracing Italians who declare only a fraction or nothing at all of their earnings — and dentists, lawyers, doctors and other big-earning professionals are frequently among the worst offenders.


Tax evasion of all types in Italy totals about euros 240 billion ($ 300 billion), or 15 percent of the country’s gross domestic product of €1.6 trillion ($ 2 trillion), tax police estimate. Winning the war on tax cheats could therefore more than wipe out the country’s budget deficit, which is expected to increase to euros 42 billion ($ 53 billion), or 2.6 percent of GDP this year. That would start knocking away at the nation’s colossal public debt of €2 trillion ($ 2.5 trillion), or 125 percent of GDP.


But “big international frauds are up,” lamented Lt. Col. Gianluca Campana, in charge of the income tax unit revenue protection office at the Guardia di Finanza, Italy’s financial police corps which reports to the Economy Ministry.


The entrenched practice by many cafes, eateries, hair dressers and similar small business of neglecting to give customers mandatory cash register receipts commonly grabs the attention in crackdowns on tax evasion in Italy.


But, cautioned Campana, “one false (big business) invoice can equal no cash register receipts for coffees for two months.”


Over all of 2011, the total of non-declared income discovered by tax police amounted to some €50 billion ($ 65 billion), of which some 20 percent was due to international tax evasion, he said. By comparison, in the first nine months of this year, tax police discovered some €40 billion in undeclared income, with 30 percent of that blamed on international tax evasion, Campana said.


With the economic crisis shrinking bottom lines, and Italy increasingly on the hunt for big-time evasion, especially by big businesses, “there is a tendency to move capital abroad, using maneuvers apparently legal but which really are not,” Campana said. A classic technique consists of declaring one’s formal residence abroad in tax havens like Monte Carlo. Also common are companies that clearly have their business base in Italy but claim it is abroad in countries with far lower tax brackets.


Campana is armed with three degrees, including a masters in tax law from Milan’s Bocconi University, the prestigious economics institute formerly headed by Monti. He brings skills to this specialized police corps that are as finely tuned as sharp-shooting.


“We are going after the big cases (of evasion) in order to rake in more money,” Campana said.


The Ferrari-driving plumber hid some €2 million ($ 2.6 million) of his income over several years by giving his customers invoices — for jobs ranging from fixing leaks to installing new bathrooms — for the actual cost of his work, but kept a second, false registry of much lower figures for tax purposes, said Pescara tax police Col. Mauro Odorisio.


Armed with a 2008 law, authorities confiscated assets belonging to the plumber equivalent to the approximately €1 million ($ 1.3 million) they contend he owed in taxes, Odorisio said.


With Ferraris in red or yellow, and snazzy Porsches parked inside, Guardia di Finanza garages practically resemble luxury car dealerships.


The cars get sold to help recoup unpaid taxes and interest.


Overall, tax revenues in Italy were up by 4.1 percent, says the Economy Ministry, when comparing figures from the first eight months of 2012 with the same period in 2011, but much of that was due to new taxes, and not necessarily a revolution in citizens’ consciences about tax obligations.


Monti’s recipe relies heavily on taxes that are nearly impossible to avoid, such as sales tax. He also revived a property tax that his populist predecessor, Premier Silvio Berlusconi, had abolished in a promise to voters.


The ministry’s report last month noted that the property tax figured prominently in the “tendency toward growth” in tax revenues. But sales tax revenue dropped slightly despite higher sales tax rates, indicating that consumers were feeling the pinch of the stagnant economy.


The heavier fiscal burden seems to have driven some honest citizens to rebel against the engrained culture of tax evasion.


The number of phone calls from the public to the tax police’s hotline to report stores, restaurants and other businesses that didn’t give customers sales receipts has almost doubled in the first nine months of this year, compared with the same period in 2011.


It’s apparently dawning on Italians that shirking taxes in the end only costs them, in terms of ever-higher levies and cutbacks in public services.


Citizens now increasingly understand that “the lack of revenue over time caused by tax evaders forced the government to stiffen the tax burden on categories where you can’t evade taxes,” Campana said, referring to workers whose taxes are deducted from paychecks. Another area where evasion is close to impossible is real estate ownership.


Odorisio noted the crackdown included extending the statute of limitations on tax evasion from six to eight years and establishing prison as a penalty for big-time evasion.


Other weapons include a measure promoted by the Monti government that limits cash payments to no more than €1,000. Paying by credit card or personal check is a relatively new habit for Italians, who are used to carrying wads of cash in their pockets, even for big-ticket items like home renovations or vacations.


Past governments in Italy sometimes resorted to tax amnesties to try to boost revenues. But critics, contending some Italians counted on such a possibility, described that strategy as only perpetuating the tax cheat culture.


Spain hasn’t had much success with its own tax amnesty introduced by the conservative government in March. That measure, expiring soon, allows undeclared assets or those hidden in tax havens to be repatriated by paying a 10 percent tax without criminal penalty. The amnesty is estimated to recuperate far less than the expected €2.5 billion ($ 3.25 billion).


Greece saw demands for tax system reform from international rescue creditors added on to conditions for future rescue loan payments, as Greek authorities acknowledged that a high-profile campaign to crack down on major tax cheats has produced disappointing results.


The cash-strapped government over the last 10 months recovered just €19 million ($ 25 million) of the €13 billion ($ 17 billion) of arrears on the list. A prominent Greek magazine publisher recently tapped anger over rich tax evaders by publishing a list of people allegedly holding Swiss bank accounts. He was acquitted this month of breaching privacy laws.


Meanwhile, Italian tax police are chasing after cheats who have shown some of the most chutzpah about not paying their fair share of taxes, like the Padua woman who advertised on the Internet that she had a couple of “cash-only” bed and breakfast rooms to let.


Tax police discovered the lodgings are part of an apartment in public housing she was given after falsely declaring she was indigent on her annual tax forms.


____


AP reporters Derek Gatopoulos in Athens and Ciaran Giles in Madrid contributed to this report.


Europe News Headlines – Yahoo! News



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Wakeman reworks rock epic Journey to Centre of Earth
















LONDON (Reuters) – The story behind the upcoming re-issue of Rick Wakeman‘s 1974 concept albumJourney to the Center of the Earth” sounds almost as unlikely as the Jules Verne tale that inspired it.


Progressive rock veteran Wakeman had presumed the original orchestration to his chart-topping disc was lost for good when his record company MAM, where the manuscripts had been stored in boxes, was brought to its knees in the early 1980s.













Although he could have re-orchestrated the work from the original album, recorded live at the Royal Festival Hall in London in 1974, Wakeman knew it would be far from perfect.


And the original score was 55 minutes long whereas the 1974 version had to be cut to closer to 40 due to the constraints of vinyl recordings at the time.


“In about 1983 or 1984 I had an enquiry to do Journey again in America,” Wakeman recalled in a telephone interview.


“I thought ‘great’. But MAM had gone, and nobody there had any idea what had happened to all the stuff of mine,” the former Yes keyboardist told Reuters.


“Up until recently I would get phone calls to do it and I said ‘no, I can’t', there is no music any more. You just resign yourself to disappointment.”


Everything changed about four years ago when a box of papers arrived at his doorstep – a fairly regular occurrence, he explained, for a man who had been married several times and had “stuff in storage all over the place”.


Sifting through the contents, Wakeman found a pile of music that was not his own, but “something told me to empty the entire box.” At the very bottom was the long-lost conductor’s score of Journey, albeit so damp the pages were stuck together.


To this day Wakeman does not know where the box came from, and is amazed it reappeared nearly 30 years after going missing.


ORIGINAL SONGS


Once the music had been downloaded on to a computer, Wakeman set about reintroducing the songs and other sections he removed for the 1974 recording with the help of notes he had kept.


He decided to make a studio recording of the rock opera, and sought to replicate the sound of the original instruments.


For the narrator’s voice, he could not go back to David Hemmings, who died in 2003, and so invited actor Peter Egan.


The result is a re-mastered version of Journey, complete with 20 minutes of unheard music, which hits shelves on November 20. It comes in the form of a “fanback” comprising the music, a 132-page magazine and a replica of the program to the 1974 show.


For Wakeman it was a labor of love, but one he hopes will prove profitable.


“We did have record companies come forward,” the 63-year-old said. “But I don’t want an A&R (artists and repertoire) man coming in and saying it could do with this and that.


“The only way I can get this done as I believe it should be is to finance it and do it myself which we did. It broke the bank, there’s no doubt about it.”


While the concept of a rock opera based on French author Verne’s 1864 sci-fi classic may not instantly appeal to young listeners today, Wakeman believes there is a market for his latest release.


“Music audiences today don’t put a date on anything, they either like it or they don’t,” he said, adding that the “prog-rock” genre for which he is best known has made something of a comeback in recent years.


PROKOFIEV FAN


The prolific musician who has made around 100 albums and sold millions of records started piano lessons when he was seven, and at about that time the seeds of his career were sown.


“Story telling to music is something I have loved since my father took me to see ‘Peter and the Wolf’ aged eight, and (Sergei) Prokofiev became my hero,” he recalled.


By his late teens he was an established session musician and joined the band Yes in 1971 with whom he recorded the hit album “Fragile” and, the following year, “Close to the Edge”.


In 1973 he released “The Six Wives of Henry VIII” a solo concept album, and in 1974, which his official online biography calls “probably the most significant year in Rick’s career”, he made Journey and toured the world with it.


Another concept album, “The Myths and Legends of King Arthur and the Knights of the Round Table” followed in 1975, and Wakeman returned to Yes for spells throughout the 1990s.


Next week he plays six dates in South America, including the first concert performance of the new, full Journey and a rendition of The Six Wives.


The new “holy grail” following the rediscovery of Journey is to track down the original music to King Arthur, which was also lost. Wakeman is orchestrating the existing recording for a show next June, but would love to find the full score.


“All of us involved hope very much that it (Journey) makes its money back, because it would then allow me to look for the King Arthur music. We are doing a version next June and it would be lovely to say we’ve done it from the original music.”


(Reporting by Mike Collett-White, editing by Paul Casciato)


Music News Headlines – Yahoo! News



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Scientists map domestic pig’s genome
















LONDON (Reuters) – Scientists have mapped the genome of the domestic pig in a project that could enhance the animal’s use in the testing of drugs for human disease.


A study, published in science journal Nature, identified genes that could be linked with illnesses suffered by farmed pigs, providing a reference tool for selective breeding to increase their resistance to disease.













“This new analysis helps us understand the genetic mechanisms that enable high-quality pork production, feed efficiency and resistance to disease,” said Sonny Ramaswany, director of the U.S. Department of Agriculture‘s National Institute of Food and Agriculture.


“This knowledge can ultimately help producers breed high-quality swine, lower production costs and improve sustainability.”


Alan Archibald at the University of Edinburgh’s Roslin Institute in Scotland, who worked on the project with collaborators in the Netherlands and the United States, said the new genome sequence was the first good draft.


Archibald said while making sense of the analysis would take time, the benefits of genome sequencing flow through more quickly in agriculture than, for instance, human medicine, “because we can use selective breeding”.


Identifying genes responsible for diseases that are also seen in people could see pigs used more extensively for drug testing.


For instance, the inherited illness known as porcine stress syndrome, which can cause sudden death in pigs, has similarities to the human condition malignant hyperthermia which causes a fast and dangerous rise in body temperature in some people under general anesthetic.


Some of the genetic faults that pigs share with humans can be linked with conditions as varied as Alzheimer’s disease, diabetes, dyslexia, obesity and Parkinson’s disease, the researchers said.


“In total, we found 112 positions where the porcine protein has the same amino acid that is implicated in a disease in humans,” they said.


(Editing by Dan Lalor)


Seniors/Aging News Headlines – Yahoo! News



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Obama holds first press conference since reelection


President Barack Obama opened his first press conference in months — and first since the election that gave him a second term — with a vow to work with both parties in Congress to tackle the so-called "fiscal cliff" and revive the economy. He also said he had "no evidence" that the scandal that led David Petraeus to resign in disgrace from his job as CIA director had led to breaches in classified national security material.


"Right now our economy is still recovering from a very deep and damaging crisis, so our top priority has to be jobs and growth," Obama said in opening remarks in the East Room of the White House.


"Both parties can work together" to address the fiscal challenges "in a balanced and responsible way," he said, before pushing Republicans to sign on to his call for raising taxes on the richest Americans.


In response to the first question, regarding Petraeus, Obama said he had "no evidence at this point from what I've seen" that there had been any national security breaches. And the president praised the retired general, saying "we are safer because of the work dave petraeus has done."


Read More..

FBI finds classified docs in Petraeus' lover's house


Paula Broadwell, the author who allegedly had an affair with former CIA
Director David Petraeus, is suspected of storing significant amounts of
military documents, including classified material, at her home,
potentially in violation of federal law.



A source familiar with case told ABC News that Broadwell admitted to the
FBI she took the documents from secure government buildings. The
government demanded that they all be given back, and when federal agents
descended on her North Carolina home on Monday night it was a
pre-arranged meeting.



Prosecutors are now determining whether to charge Broadwell with a
crime, and this morning the FBI and military are poring over the
material. The 40-year-old author, who wrote the biography on Gen.
Petraeus "All In," is cooperating and the case, which is complicated by
the fact that as an intelligence officer in the U.S. Military Reserve
she had security clearance to review the documents.



FULL COVERAGE: David Petraeus Scandal



The FBI found classified material on a computer voluntarily handed over
by Broadwell earlier in the investigation. Prosecutors will now have to
determine how important the classified material is before making a final
decision. Authorities could decide to seek disciplinary action against
her rather than pursue charges.



Senior FBI officials are expected to brief the House and Senate
Intelligence Committees today on their handling of the Petraeus
investigation. The officials are expected to lay out how the case was
developed and argue that there were no politics involved.



The case is so critical that FBI Director Robert Mueller may attend to
defend the bureau, ABC News has learned. Members of Congress have been
angry that they were not informed about the case before the story was
reported by the media, but FBI officials maintain that their guidelines
forbid them from discussing ongoing criminal cases.



This summer, Florida socialite and "honorary ambassador" to the military Jill Kelley
received anonymous emails accusing her of flaunting a friendly
relationship with military brass in Tampa. Kelley then called the FBI,
which traced those emails back to Broadwell's computer. Investigators
are said to have then found emails in Broadwell's inbox that pointed to
an intimate affair with Petraeus, who on Friday admitted to the affair
and announced his resignation as CIA director.



See the timeline of the Petraeus/Broadwell affair HERE.



The FBI has now uncovered "potentially inappropriate" emails between
Gen. John Allen, the commander of American forces in Afghanistan, and
Kelley, according to a senior U.S. defense official who is traveling with
Defense Secretary Leon Panetta. The department is reviewing between
20,000 and 30,000 documents connected to this matter, the official said.
The email exchanges between Kelley and Allen took place from 2010 to
2012.




The U.S. official said the emails were "innocuous" and mostly about
upcoming dinner parties and seeing him on TV. Allen denies he was
involved in an affair, a Pentagon official said. An intermediary for
Allen told ABC News that Allen and his wife are friends with Kelley and
her husband and most of the emails were sent from Kelley to Allen's
wife.

A U.S. official said Allen may have triggered the investigation when he
got an anonymous email a few months ago that was traced to Broadwell.
The email had a "Kelley Patrol" return address or subject line and
painted Kelley as a seductress, which Allen found alarming and mentioned
to Kelley in a subsequent email, the official said.



The official described Kelley as a "nice, bored rich socialite who drops
the honorary from her title... and tells people she is an ambassador.
She gets herself in anything related to Centcom and all the senior
people and has been for years."

MORE: Jill Kelley and Twin Closely Tied to Top Brass






Leon Panetta: 'No One Should Leap to Any Conclusions' Regarding Gen. Allen



Panetta cautioned that "no one should leap to any conclusions" about allegations against Allen over the investigation.



Panetta said he supports Allen, who has been in command in Kabul since
July 2011. He took over that summer for Petraeus, who retired from the
Army to take over as the head of the CIA.



"He certainly has my continued confidence to lead our forces and to
continue the fight," Panetta said at a news conference in Perth,
Australia, Wednesday.



Panetta declined to explain the nature of Allen's correspondence with
Kelley, connected to the scandal that led to Petraeus' resignation last
week as director of the CIA.



Secretary of State Hillary Rodham Clinton, who appeared with Panetta,
declined to comment on the Allen case, but insured the scandal has not
harmed the war effort.



"There has been a lot of conversation, as you might expect, but no
concern whatsoever being expressed to us because the mission has been
set forth and it's being carried out," Clinton said.



Allen had been nominated as the next commander of U.S. European Command
and the commander of NATO forces in Europe, and despite President
Obama's backing, the nomination has been put on hold. The change of
command at NATO is currently slated to not take place until March at the
earliest.



Allen was supposed to appear before a Senate confirmation hearing this
Thursday alongside his designated replacement, Marine Gen. Joseph
Dunford. Panetta said that while the matter is being investigated by
the Defense Department IG, Allen will remain in his post as commander of
the International Security Assistance Force, based in Kabul.

Also Read
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When Facebook insiders, employees can sell stock
















On Wednesday, additional Facebook stock became eligible for sale for the first time. It follows the expiration of similar lock-up periods in August and October. Other shares will become eligible for sale in the coming months.


Up to 1.56 billion more shares could flood the stock market — nearly four times the 421 million shares that had been trading since Facebook’s initial public offering in May. The 1.56 billion figure includes shares released from lock-up already.













On Aug. 16, a lock-up period expired for 271 million shares held by early investors and directors who had participated in the IPO, though CEO Mark Zuckerberg was excluded for unspecified reasons.


On Oct. 29, the lock-up ended for 234 million shares and stock options held by employees as of Oct. 15, excluding Zuckerberg. Oct. 31 was the first trading day since then because of stock market closures resulting from Superstorm Sandy.


On Wednesday, another 852 million shares and stock options became eligible. Zuckerberg had been eligible to sell his shares at this date, but Facebook has changed that given that the CEO had no plans to do so until at least next September.


Here’s the schedule for remaining lock-up expirations, as reported by Facebook Inc. in regulatory filings:


— Dec. 14: 156 million shares held by early investors and others who participated in IPO, except Zuckerberg.


— May 18, 2013: 47 million shares held by the Russian Internet company Mail.ru Group and DST Global, both of which made early investments in Facebook.


Social Media News Headlines – Yahoo! News



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Inyecciones epidurales de esteroides no alivian dolor del nervio ciático
















NUEVA YORK (Reuters Health) – Las inyecciones de esteroides


no alivian la ciática, un trastorno común causante de dolor de













piernas y espalda baja, según muestra una revisión de la


literatura médica.


Tras analizar casi dos decenas de estudios sobre miles de


pacientes, un equipo de Australia determinó que las inyecciones


epidurales (en la médula) de corticoesteroides no tenían un


efecto inmediato o prolongado en la neuralgia del nervio ciático


y el alivio pasajero del dolor en las piernas sería


insignificante para los pacientes.


“Queda muy claro que el tratamiento no es una buena opción”,


dijo el coautor del estudio, Chris Maher, del Instituto George


para la Salud Mundial, Sídney, Australia.


Aun así, el uso de las inyecciones epidurales de esteroides


para tratar los dolores de espalda en los pacientes de Medicare


crecieron de 741.000 en el 2000 a casi 1.438.000 en el 2004.


En Estados Unidos, una inyección cuesta varios cientos de


dólares. Y una partida fallada de uno de los esteroides


utilizados en los estudios revisados, la metilprednisolona,


acaba de causar en el país un brote de meningitis fúngica que


infectó al menos a 400 personas y provocó 31 muertes.


Estudios previos ya habían cuestionado la efectividad de las


inyecciones epidurales de esteroides para tratar la ciática, que


comúnmente se atribuye al daño de un nervio.


Ahora, el equipo de Maher reunió los resultados de los


ensayos clínicos de mejor calidad, aleatorizados, para incluir


finalmente 23 estudios sobre un total de 2300 pacientes. El


nivel de dolor se había evaluado con una escala de cero a 100 (a


mayor puntaje, peor dolor).


El equipo observó que las inyecciones no aliviaban el dolor


de espalda de la ciática en el corto o el largo plazo. En cuanto


al dolor de piernas, sólo en el corto plazo (entre dos semanas y


tres meses) surgió una reducción estadísticamente significativa


de seis puntos.


“En una escala de 100 puntos, seis parecen una diferencia


mínima y, para nosotros, quizás ni tenga importancia clínica”,


dijo Maher. “Pensamos que la pregunta está respondida (…) De


modo que en cuanto a la investigación, hay que avanzar sobre


otros tratamientos de la ciática”.


Maher sostuvo que, en lugar de utilizar las inyecciones de


esteroides, los pacientes con ciática deberían consultar al


médico. Otras opciones terapéuticas son los analgésicos comunes,


como el acetaminofeno, que son fármacos que actúan en el sistema


nervioso. La última opción es la cirugía.


FUENTE: Annals of Internal Medicine, online 12 de noviembre


del 2012


Seniors/Aging News Headlines – Yahoo! News



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