Twin explosions strike southern Syrian city

BEIRUT (AP) — Syria‘s state-run news agency says two large explosions have struck the southern city of Daraa, causing multiple casualties and heavy material damage.

SANA did not immediately give further information or say what the target of Saturday’s explosions was.

The Britain-based Syrian Observatory for Human Rights says the blasts went off near a branch of the country’s Military Intelligence in Daraa.

The Observatory, which relies on a network of activists on the ground, says the explosions were followed by clashes between regime forces and rebels fighting to topple President Bashar Assad.

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Philip Roth Is Retiring; Amazon Glitch Disables Buy Buttons

Today in books and publishing: Philip Roth confirms his retirement; Amazon‘s mysteriously vanishing buy buttons; Kobo expands to Italy, Kindle considers China; cities in literature.

RELATED: Trikes, a Mustache, and Andy Warhol

Philip Roth wraps it up. One of America’s most celebrated living novelists has been hinting at retirement for a while now. But he didn’t choose to make a big announcement in a prominent stateside literary organ like The New York Review of Books. He chose instead to let it out in interviews with the foreign press over recent weeks. Last month he told Nelly Kaprièlian of French magazine Les Inrockuptibles that he hasn’t written new material in three years, and doesn’t plan to write any new novels. “To tell you the truth, I’m done,” he said frankly, “Nemesis will be my last book … Enough is enough! I no longer feel this fanaticism to write that I have experienced in my life.” He said the same thing in an interview with Italian magazine La Repubblica earlier this month. His publisher Houghton Mifflin confirmed that Roth is entering retirement. It looks the 74-year-old writer will have plenty of time to go over his life story and thoughts on literature with his new biographer, Blake Bailey. [Salon]

RELATED: How to Game Amazon Prime; Random House Consolidates in the Spanish Market

Where did Amazon‘s buy buttons go? Late last night, customers looking to replenish their Kindles with fresh e-books were probably quite frustrated. No matter how hard anyone clicked, there was no way to purchase e-books from Penguin, Random House, Macmillan, Simon & Schuster, Hachette, and HarperCollins through Amazon. A company spokesperson later confirmed that it was just a technical slip-up, and buy buttons were quickly restored. But given Amazon’s propensity to punish publishers that don’t bend to its will with disabled buy buttons, this brief black-out set off a minor panic in publishing land. Why were only Big Six publishers affected? Did it have anything to do with the ongoing agency pricing legal battles or the Penguin Random House merger? Though it seems to have been nothing more serious than a technical goof, it’s a stark reminder that Amazon has the ability—as well as the leverage—to shut down publishers’ most important connection with consumers at the click of a mouse. [New York Observer]

RELATED: Chart: The Rapid Gains of the E-book

E-reading takes a global turn. E-books may be taking firm holds in the U.S., but they have a long way to go before they became the global format of choice for readers. Italy may be going in an increasingly digital direction soon, with the country’s largest bookseller Mondadori Group partnering with Kobo to stock Touch e-readers in its hundreds of stores. 34,000 e-books will be available for Italian readers. China is another largely untapped market, one that Amazon is eyeing enviously. ZDNet’s Liau Yun Qing reports that Kindles may become available there as early as this month. “If Amazon brings its e-reader to China, it will face competition from Chinese e-commerce player Dangdang which launched its e-reader in July at a retail price of 599 yuan (US$ 79),” she writes. “In comparison, the cheapest Kindle Paperwhite e-reader, which includes “Special Offers”, retails at US$ 119 in the United States.” [ZDNet]

RELATED: New Batman Comic Postponed; Books Banned in China Thrive in Hong Kong

Cities in literature. Mark Binelli’s new book Detroit City Is the Place to Be is all about the Motor City—its ascent during America’s industrial golden age, and its struggle to redefine itself. Given his obsession with the urban, Publishers Weekly decided to tap Binelli for a list of his favorite books that take specific cities as a central theme. It’s more interesting than most lists on this subject might have been. For instance, he shines a light on Joan Didion not for her classic takes on San Francisco or New York, but for her book Miami. And his favorite books to take on New York—Ben Katchor’s The Jew of New York and Joseph Mitchell’s Up in the Old Hotel—are refreshing inclusions. His favorite book about Detroit, Elmore Leonard’s City Primeval, is also a bit surprising. [Publishers Weekly]

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Weinstein Co., Clear Channel, Madison Square Garden Hosting Benefit Concert for Sandy Relief

LOS ANGELES (TheWrap.com) – Clear Channel Media, The Madison Square Garden Company and The Weinstein Company are joining together to produce a benefit concert to raise money for victims of Hurricane Sandy.

The concert, titled “12-12-12,” will feature live music, although the producers did not reveal who would be performing. The roster should be an A-list one though, given that this is the same group of corporate entities that backed “The Concert for New York City,” a star-studded affair with the likes of The Who and Billy Joel on hand to raise money for 9/11.

The concert for Sandy Relief will be held on December 12, 2012, at Madison Square Garden in New York, and the money raised will be dispensed through the Robin Hood Relief Fund.

Hurricane Sandy slammed into the Eastern Seaboard last week, leaving 110 people dead and more than 1 million without power. Damage from the storm is estimated to be between $ 30 billion to $ 50 billion in economic losses.

“12-12-12″ will be produced by James Dolan, executive chairman of The Madison Square Garden Company; John Sykes, president of Clear Channel Entertainment Enterprises; and Harvey Weinstein, co-founder and chairman of The Weinstein Company.

In a joint statement, the producers said: “The Concert for New York City was a night filled with emotion, courage and tremendous hope when we came together as a city following the 9/11 attack. Once again, our city, as well as millions of our neighbors in the tri-state area, are in desperate need of our assistance as they recover from Hurricane Sandy and rebuild their lives. We have no doubt that the event we are planning will be filled with unforgettable music, entertainment and that uniquely American spirit of community, compassion and generosity.”

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Gilead posts positive results in mid-stage Hepatitis C study

(Reuters) – Gilead Sciences Inc on Saturday reported a 100 percent cure rate using a combination of drugs in a small number of patients with the most common and hardest to treat form of hepatitis C.

Rival Abbott Laboratories Inc, meanwhile, said a trio of its oral medicines to treat hepatitis C produced unprecedented cure rates in a larger number of patients who had failed to benefit from standard treatment, as well as very high cure rates for newly treated patients.

Data from both companies’ mid-stage trials were released Saturday at the annual meeting of the American Association for the Study of Liver Disease in Boston.

Gilead’s study, dubbed Electron, examined 25 patients with genotype 1 chronic hepatitis C virus (HCV) infection who were treated for 12 weeks with a combination of three drugs: sofosbuvir, ribavirin and GS-5885.

GS-5885 is from a promising new class of drugs known as NS5A inhibitors, which prevent the hepatitis C virus from replicating.

The infection was undetectable four weeks after completing therapy in all of the patients who had never received this combination of drugs before, Gilead said.

The drugs generally were well tolerated in the study, Gilead said.

In the sofosbuvir combined with GS-5885 and ribavirin patient groups, one patient dropped out because of an adverse side effect that the company said was unrelated to the drugs.

Sofosbuvir and GS-5885 are still being studied for their safety and efficacy.

The biopharmaceutical company will present the data on Tuesday at the annual meeting of the American Association for the Study of Liver Diseases in Boston.

Mark Schoenebaum, a biotech analyst with ISI Group, said in a research note that he expects Gilead shares to rise on Monday based on these “best case” results.

UBS analyst Matthew Roden said “these data strongly support Gilead’s leadership position” in the hepatitis C virus space.

Gilead recently started the first Phase 3 trial evaluating a fixed-dose combination of sofosbuvir and GS-5885 in patients with genotype 1 chronic hepatitis C virus infection who had not received these drugs before.

This study is evaluating the fixed-dose combination with and without ribavirin for 12- and 24-weeks in 800 patients, 20 percent of whom have evidence of cirrhosis, or liver scarring.

(Reporting By Debra Sherman; Editing by Vicki Allen)

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Four days later, Obama wins Florida

ST. PETERSBURG, Fla. - President Barack Obama was declared the winner of Florida's 29 electoral votes Saturday, ending a four-day count with a razor-thin margin that narrowly avoided an automatic recount that would have brought back memories of 2000.

No matter the outcome, Obama had already clinched re-election and now has 332 electoral votes to Romney's 206.

The Florida Secretary of State's Office said that with almost 100 per cent of the vote counted, Obama led Republican challenger Mitt Romney 50 per cent to 49.1 per cent, a difference of about 74,000 votes. That was over the half-per cent margin where a computer recount would have been automatically ordered unless Romney had waived it.

There is a Nov. 16 deadline for overseas and military ballots, but under Florida law, recounts are based on Saturday's results. Only a handful of overseas and military ballots are believed to remain outstanding.

It's normal for election supervisors in Florida and other states to spend days after any election counting absentee, provisional, military and overseas ballots. Usually, though, the election has already been called on election night or soon after because the winner's margin is beyond reach.

But on election night this year, it was difficult for officials — and the media — to call the presidential race here, in part because the margin was so close and the voting stretched into the evening.

In Miami-Dade, for instance, so many people were in line at 7 p.m. in certain precincts that some people didn't vote until after midnight.

The hours-long wait at the polls in some areas, a lengthy ballot and the fact that Gov. Rick Scott refused to extend early voting hours has led some to criticize Florida's voting process. Some officials have vowed to investigate why there were problems at the polls and how that led to a lengthy vote count.

If there had been a recount, it would not be as difficult as the lengthy one in 2000. The state no longer uses punch-card ballots, which became known for their hanging chads. All 67 counties now use optical scan ballots where voters mark their selections manually.

Republican George W. Bush won the 2000 contest after the Supreme Court declared him the winner over Democrat Al Gore by a scant 537 votes.

The win gave Obama victories in eight of the nine swing states, losing only North Carolina. In addition to Florida, he won Ohio, Iowa, New Hampshire, Wisconsin, Virginia, Colorado and Nevada.

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How 'poor judgment' felled military star Petraeus

WASHINGTON (Reuters) - David Petraeus was a star on the battlefield, commanding the Iraq and Afghanistan wars, but was undone by "poor judgment" in engaging in an extramarital affair that led to his downfall as CIA director.

Just two days after his 60th birthday, Petraeus stepped down from the spy agency where he had held the top office since September 6, 2011.

"After being married for over 37 years, I showed extremely poor judgment by engaging in an extramarital affair. Such behavior is unacceptable, both as a husband and as the leader of an organization such as ours. This afternoon, the President graciously accepted my resignation," Petraeus told the shadow warriors he commanded at CIA.

It was a stunning downfall for a revered military man who was seen as one of the top American leaders of his generation and was once considered a potential contender for the White House.

Petraeus was credited with pulling Iraq from the brink of all-out civil war and for battlefield successes in Afghanistan after overseeing a surge of 30,000 troops ordered by President Barack Obama in late 2009. He became known for counter-insurgency strategies that were seen as gaining ground against the Taliban in Afghanistan.

"I don't think he was professionally overrated. His were genuine accomplishments," said James Carafano, a war historian with the conservative Heritage Foundation think tank.

At the time of his nomination to the CIA post, some Washington insiders had said the White House wanted to find a prominent position for Petraeus to ensure he would not be recruited by Republicans as a challenger to the 2012 Obama-Biden ticket.

When he was nominated to lead the CIA there were some concerns in intelligence circles that the high-profile four-star Army general might not be able to lead from the shadows as appropriate for a spy chief.

But once he took over the head office at the U.S. spy agency, Petraeus kept a decidedly low public profile.

Senate Intelligence Committee Chairman Dianne Feinstein, a Democrat, expressed regret about the resignation of "one of America's best and brightest" and said it was an "enormous loss" for the country.

"At CIA, Director Petraeus gave the agency leadership, stature, prestige and credibility both at home and abroad. On a personal level, I found his command of intelligence issues second to none," she said.

RESIGNATION ACCEPTED

After accepting his resignation about a year-and-a-half after nominating Petraeus to the CIA post, Obama said: "By any measure, he was one of the outstanding General officers of his generation, helping our military adapt to new challenges, and leading our men and women in uniform through a remarkable period of service in Iraq and Afghanistan, where he helped our nation put those wars on a path to a responsible end."

Earlier this week, in a Newsweek article entitled "General David Petraeus's Rules for Living," he listed 12 lessons for leadership. Number 5 was: "We all will make mistakes. The key is to recognize them and admit them, to learn from them, and to take off the rear­ view mirrors - drive on and avoid making them again."

In 2010 Petraeus stepped into the breach as the new commander of U.S. forces in Afghanistan to replace General Stanley McChrystal who was fired by Obama in a scandal over an article in which McChrystal and his aides made mocking comments about the president and some of his top advisers.

In 2009 Petraeus was diagnosed with early-stage prostate cancer and underwent radiation treatment. The media-friendly general joked at that time at a Washington event that reporters were only gathered "to see if the guy is still alive."

Petraeus, born in Cornwall, New York, lives in Virginia with his wife Holly. They have two grown children, a son who was an Army Ranger who served in Afghanistan, and a daughter.

Petraeus's wife, Holly, is an activist and volunteer who champions military families, and she continued that work after her husband retired from the military and moved to the CIA.

She currently is assistant director of the office of servicemember affairs at the Consumer Financial Protection Bureau, where she tries to keep unscrupulous lenders from taking advantage of military personnel. The bureau was championed by Harvard law professor Elizabeth Warren, who was elected to the Senate from Massachusetts this week.

Holly Petraeus is the daughter of four-star General William Knowlton, who was superintendent of the U.S. Military Academy at West Point when Petraeus was a cadet.

She briefed the press at the Pentagon on her efforts recently and was introduced by Defense Secretary Leon Panetta, who called her "a true friend of the Department of Defense and a dedicated member of our military family."

Petraeus has four Defense Distinguished Service Medal awards, three Distinguished Service Medal awards, the Bronze Star Medal for valor, and the State Department Distinguished Service Award.

He has a doctorate in international relations from Princeton University.

(Additional reporting by David Alexander, Matt Spetalnick and Diane Bartz; Editing by Warren Strobel and Jackie Frank)

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Philip Roth Is Retiring; Amazon Glitch Disables Buy Buttons

Today in books and publishing: Philip Roth confirms his retirement; Amazon‘s mysteriously vanishing buy buttons; Kobo expands to Italy, Kindle considers China; cities in literature.

RELATED: Trikes, a Mustache, and Andy Warhol

Philip Roth wraps it up. One of America’s most celebrated living novelists has been hinting at retirement for a while now. But he didn’t choose to make a big announcement in a prominent stateside literary organ like The New York Review of Books. He chose instead to let it out in interviews with the foreign press over recent weeks. Last month he told Nelly Kaprièlian of French magazine Les Inrockuptibles that he hasn’t written new material in three years, and doesn’t plan to write any new novels. “To tell you the truth, I’m done,” he said frankly, “Nemesis will be my last book … Enough is enough! I no longer feel this fanaticism to write that I have experienced in my life.” He said the same thing in an interview with Italian magazine La Repubblica earlier this month. His publisher Houghton Mifflin confirmed that Roth is entering retirement. It looks the 74-year-old writer will have plenty of time to go over his life story and thoughts on literature with his new biographer, Blake Bailey. [Salon]

RELATED: How to Game Amazon Prime; Random House Consolidates in the Spanish Market

Where did Amazon‘s buy buttons go? Late last night, customers looking to replenish their Kindles with fresh e-books were probably quite frustrated. No matter how hard anyone clicked, there was no way to purchase e-books from Penguin, Random House, Macmillan, Simon & Schuster, Hachette, and HarperCollins through Amazon. A company spokesperson later confirmed that it was just a technical slip-up, and buy buttons were quickly restored. But given Amazon’s propensity to punish publishers that don’t bend to its will with disabled buy buttons, this brief black-out set off a minor panic in publishing land. Why were only Big Six publishers affected? Did it have anything to do with the ongoing agency pricing legal battles or the Penguin Random House merger? Though it seems to have been nothing more serious than a technical goof, it’s a stark reminder that Amazon has the ability—as well as the leverage—to shut down publishers’ most important connection with consumers at the click of a mouse. [New York Observer]

RELATED: Chart: The Rapid Gains of the E-book

E-reading takes a global turn. E-books may be taking firm holds in the U.S., but they have a long way to go before they became the global format of choice for readers. Italy may be going in an increasingly digital direction soon, with the country’s largest bookseller Mondadori Group partnering with Kobo to stock Touch e-readers in its hundreds of stores. 34,000 e-books will be available for Italian readers. China is another largely untapped market, one that Amazon is eyeing enviously. ZDNet’s Liau Yun Qing reports that Kindles may become available there as early as this month. “If Amazon brings its e-reader to China, it will face competition from Chinese e-commerce player Dangdang which launched its e-reader in July at a retail price of 599 yuan (US$ 79),” she writes. “In comparison, the cheapest Kindle Paperwhite e-reader, which includes “Special Offers”, retails at US$ 119 in the United States.” [ZDNet]

RELATED: New Batman Comic Postponed; Books Banned in China Thrive in Hong Kong

Cities in literature. Mark Binelli’s new book Detroit City Is the Place to Be is all about the Motor City—its ascent during America’s industrial golden age, and its struggle to redefine itself. Given his obsession with the urban, Publishers Weekly decided to tap Binelli for a list of his favorite books that take specific cities as a central theme. It’s more interesting than most lists on this subject might have been. For instance, he shines a light on Joan Didion not for her classic takes on San Francisco or New York, but for her book Miami. And his favorite books to take on New York—Ben Katchor’s The Jew of New York and Joseph Mitchell’s Up in the Old Hotel—are refreshing inclusions. His favorite book about Detroit, Elmore Leonard’s City Primeval, is also a bit surprising. [Publishers Weekly]

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Abbott hepatitis C drugs bring high cure rates in trial

(Reuters) – A trio of oral medicines from Abbott Laboratories Inc to treat hepatitis C produced unprecedented cure rates in patients who had failed to benefit from standard treatment, as well as very high cure rates for newly treated patients, Abbott said on Saturday.

Detailed data from the mid-stage trial, called Aviator, were released Saturday at the annual meeting of the American Association for the Study of Liver Disease (AASLD) in Boston.

Investors and patients have very high hopes for the Abbott drugs – a protease inhibitor called ABT-450, a polymerase inhibitor ABT-333 and ABT-267 from a class known as NS5A inhibitors. They are used without interferon, an injectable standard treatment that causes flu-like symptoms.

Abbott said it plans to move ahead with large Phase III studies of the three drugs, used either with or without the standard antiviral pill ribavirin, based on favorable results seen in patients treated for eight weeks or twelve weeks in the Aviator study. Patients in the study had the most common, and hardest-to-treat, strain of hepatitis C known as Genotype 1.

Some 93 percent of patients who failed prior therapy had a sustained virologic response (SVR), meaning they were considered cured, after 12 weeks of taking the trio of new drugs, plus ribavirin.

“Nobody anywhere has broken the 50 percent mark in (cure rates) for this population,” Scott Brun, a senior Abbott research executive said in an interview. “These are robust results.”

Abbott said it aims to be the first company to market an interferon-free regimen to patients with Genotype 1 infections.

Four of 448 patients in the study discontinued treatment due to adverse events, a dropout rate that Abbott said suggested the medicines were very well tolerated.

About 97 percent of previously untreated patients were considered cured after 12 weeks of treatment with the three Abbott drugs, plus ribavirin. Moreover, similarly impressive cure rates were seen among patients taking the three drugs, plus ribavirin, for 8 weeks.

Without ribavirin, 87 percent of previously untreated patients were considered cured after 12 weeks on Abbott’s three drugs, Abbott said.

A pair of new hepatitis C drugs approved last year, Vertex Pharmaceuticals Inc’s Incivek and Merck & Co’s Victrelis, significantly boosted cure rates and cut treatment duration to as low as 24 weeks for some patients. But the protease inhibitors must still be taken with interferon, an injected drug that often causes severe flu-like symptoms that lead many hepatitis patients to delay or discontinue treatment.

Gilead Sciences Inc, Bristol-Myers Squibb Co and Vertex are racing to develop interferon-free treatment regimens. They are expected to become blockbuster products, if approved, because of their far shorter treatment times and better cure rates, compared with existing drug regimens.

Many analysts view Gilead as current leader both on timing and perceived advantages of its experimental hepatitis C program.

An estimated 3 million Americans are believed infected with the virus, which quietly damages the liver over years or decades and is the biggest reason for liver transplants in the United States. Abbott said as many as 170 million people worldwide are infected.

(Reporting By Ransdell Pierson; Editing by Vicki Allen)

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Twin explosions strike southern Syrian city

BEIRUT (AP) — Syria‘s state-run news agency says two large explosions have struck the southern city of Daraa, causing multiple casualties and heavy material damage.

SANA did not immediately give further information or say what the target of Saturday’s explosions was.

The Britain-based Syrian Observatory for Human Rights says the blasts went off near a branch of the country’s Military Intelligence in Daraa.

The Observatory, which relies on a network of activists on the ground, says the explosions were followed by clashes between regime forces and rebels fighting to topple President Bashar Assad.

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Chen Guang-who? Chinese official claims ignorance of blind activist

BEIJING (Reuters) – Despite causing a huge diplomatic incident between the world’s two largest economies earlier this year, the Chinese official in charge of the hometown of blind legal activist Chen Guangcheng said on Friday that he has no idea who he was.

Chen, one of China’s most prominent human rights advocates, slipped away from under the noses of guards and eyes and ears of surveillance equipment around his village home near Linyi in eastern Shandong province in late April.

He then sought refuge at the U.S. embassy in Beijing for six days, embarrassing China and creating an awkward backdrop for U.S. Secretary of State Hillary Clinton’s visit which happened to fall at the same time.

But asked on the sidelines of a party congress in Beijing about Chen, Linyi’s Communist Party boss Zhang Shaojun deadpanned.

“I’ve never heard (of him),” Zhang told Reuters, before hurrying away into a closed-door meeting.

In May, Chen told Reuters that an unnamed central government official had promised to investigate accusations that local officials engineered his jailing on false charges and subsequent 19 months of extra-judicial house arrest and abuse.

But Zhang, a portly man with thinning hair, said he knew of no such investigation.

“I’ve never heard of this matter,” he said.

Robbed of his sight as a child, the rural-born Chen taught himself law and drew international attention in 2005 after accusing officials of enforcing late-term abortions and sterilizations.

Following intense negotiations between Chinese and U.S. officials, Chen left the embassy and was allowed to apply for a visa to study abroad. He is currently a visiting fellow at the New York University School of Law.

(Reporting by Gabriel Wildau; Editing by Ben Blanchard)

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Assad says will live and die in Syria

DOHA (Reuters) – President Bashar al-Assad said he would “live and die” in Syria and warned that any Western invasion to topple him would have catastrophic consequences for the Middle East and beyond.

Assad’s defiant remarks coincided with a landmark meeting in Qatar on Thursday of Syria’s fractious opposition to hammer out an agreement on a new umbrella body uniting rebel groups inside and outside Syria, amid growing international pressure to put their house in order and prepare for a post-Assad transition.

The Syrian leader, battling a 19-month old uprising against his rule, appeared to reject an idea floated by British Prime Minister David Cameron on Tuesday that a safe exit and foreign exile for the London-educated Assad could end the civil war.

“I am not a puppet. I was not made by the West to go to the West or to any other country,” he told Russia Today television in an interview to be broadcast on Friday. “I am Syrian; I was made in Syria. I have to live in Syria and die in Syria.”

Russia Today’s web site, which published a transcript of the interview conducted in English, showed footage of Assad speaking to journalists and walking down stairs outside a white villa. It was not clear when he had made his comments.

The United States and its allies want the Syrian leader out, but have held back from arming his opponents or enforcing a no-fly zone, let alone invading. Russia has stood by Assad.

The president said he doubted the West would risk the global cost of intervening in Syria, whose conflict has already added to instability in the Middle East and killed some 38,000 people.

“I think that the price of this invasion, if it happened, is going to be bigger than the whole world can afford … It will have a domino effect that will affect the world from the Atlantic to the Pacific,” the 47-year-old president said.

“I do not think the West is going in this direction, but if they do so, nobody can tell what is next.”

QATAR, TURKEY CHIDE OPPOSITION

Backed by Washington, the Doha talks underline Qatar’s central role in the effort to end Assad‘s rule as the Gulf state, which funded the Libyan revolt to oust Muammar Gaddafi, tries to position itself as a player in a post-Assad Syria.

Qatari Prime Minister Hamad bin Jassim Al Thani urged the Syrian opposition to set its personal disputes aside and unite, according to a source inside the closed-door session.

“Come on, get a move on in order to win recognition from the international community,” the source quoted him as saying.

Turkish Foreign Minister Ahmed Davutoglu delivered a similar message, saying, according to the source: “We want one spokesman not many. We need efficient counterparts, it is time to unite.”

An official text of a speech by Qatari Foreign Minister Khalid Mohamed al-Attiyah showed he told the gathering: “The Syrian people awaits unity from you, not divisions … Your agreement today will prove to the international community that there is a unity … and this will reflect positively in the international community’s stance towards your fair cause.”

Across Syria, more than 90 people were killed in fighting on Thursday, the Syrian Observatory for Human Rights said.

In Turkey’s Hatay border province, two civilians, a woman and a young man, were wounded by stray bullets fired from Syria, according to a Turkish official. Turkish forces increased their presence along the frontier, where officials have said they might seek NATO deployment of ground to air missiles.

Syria poses one of the toughest foreign policy challenges for U.S. President Barack Obama as he starts his second term.

International rivalries have complicated mediation efforts. Russia and China have vetoed three Western-backed U.N. Security Council resolutions that would have put Assad under pressure.

Syria’s conflict, pitting mostly Sunni Muslim rebels against forces dominated by Assad’s Alawite minority, whose origins lie in Shi’ite Islam, has fuelled sectarian tensions across the Middle East. Sunni Arab countries and Turkey favor the rebels, while Shi’ite Iran backs Assad, its main Arab ally.

“VICIOUS CIRCLE”

The main opposition body, the Syrian National Council (SNC), has been heavily criticized by Western and Arab backers of the revolt as ineffective, run by exiles out of touch with events in Syria, and under the sway of the Islamist Muslim Brotherhood.

British Foreign Minister William Hague said London would now talk to rebel groups inside Syria, after U.S. Secretary of State Hillary Clinton last week criticized the SNC and called for a new opposition body to include those “fighting and dying”.

But the plan for a body that could eventually be considered a government-in-waiting capable of winning foreign recognition and therefore more military backing ran into trouble almost as soon as it was proposed by SNC member Riyad Seif.

The meeting has so far been bogged down by arguments over the SNC representation and the number of seats the rival groups – which include Islamists, leftists and secularists – will have in a proposed assembly. Seif said he hoped for agreement on that on Thursday night, although the talks may continue into Friday.

Senior SNC member Burhan Ghalioun said the participants were moving towards consensus: “The atmosphere was positive. We all agree that we don’t want to walk away from this meeting in failure,” he told reporters.

Seif’s proposal is the first concerted attempt to merge opposition forces to help end the devastating conflict.

The initiative would also create a Supreme Military Council, a Judicial Committee and a transitional government-in-waiting of technocrats – along the lines of Libya’s Transitional National Council, which managed to galvanize international support for its successful battle to topple Gaddafi.

Michael Doran of the Brookings Institute in Washington told a forum in Doha it would not work for Syria. “It’s not a ridiculous idea, but it’s not going to succeed,” he said.

A diplomat on the sidelines of the talks said international divisions in the U.N. Security council did not help.

“It’s a vicious circle. They are asking the opposition to unite when they admit they are not themselves united,” he said.

(Writing by Tom Perry and Samia Nakhoul; Editing by Alistair Lyon, Alastair Macdonald and Philippa Fletcher)

World News Headlines – Yahoo! News

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‘NBA 2K13′ tops video games titles in October

NEW YORK (AP) — U.S. retail sales of new video game hardware, software and accessories fell 25 percent in October, marking the 11th straight month of declining sales for physical game products, according to a report from NPD Group.

Many gamers are waiting for big holiday releases such as Activision‘s “Call of Duty: Black Ops II.”

NPD said sales fell to $ 755.5 million from $ 1 billion a year earlier. Sales of video games themselves, excluding PC titles, fell 25 percent to $ 432.6 million. Sales of hardware such as Microsoft‘s Xbox 360 fell 37 percent to $ 187.3 million. Sales of accessories, meanwhile, grew 5 percent to $ 135.6 million.

Thursday’s study from NPD Group tracks sales of new physical products — about 50 percent of the total spending. Excluded are sales of used games and rentals as well as digital and social-network spending.

NPD also listed the top-selling games in October:

1. “NBA 2K13,” Take-Two Interactive Software Inc.

2. “Resident Evil 6,” Capcom USA

3. “Pokemon Black Version 2,” Nintendo Co.

4. “Dishonored,” Bethesda Softworks

5. “Pokemon White Version 2,” Nintendo Co.

6. “Madden NFL 13,” Electronic Arts Inc.

7. “FIFA Soccer 13,” Electronic Arts Inc.

8. “Medal of Honor: Warfighter,” Electronic Arts Inc.

9. “Borderlands 2,” Take-Two Interactive Software Inc.

10. “Skylander Giants,” Activision Blizzard Inc.

Gaming News Headlines – Yahoo! News

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On Twitter, pope to get different type of followers

VATICAN CITY (Reuters) – Pope Benedict already has 1.2 billion “followers” in the standard sense of the word but he soon will have another type when he enters what for any 85 year old is the brave new world of Twitter.

Vatican officials say the pontiff, who is known not to love computers and still writes most of his speeches by hand, will have his own handle by the end of the year.

“It will be an officially verified channel,” said a Vatican official.

Primarily the tweets will come from the contents of his weekly general audience, Sunday blessings and homilies on major Church holidays. They will also include reaction to major world events, such as natural disasters.

The leader of the world’s 1.2 billion or so Roman Catholics will not, of course, write the tweets himself, but he will sign off on them before they are sent in his name.

But even divine intervention might not help squeeze the gist of a papal encyclical, which can run to more than 140 pages, into 140 characters.

Those tweets will probably be limited to a link to a url with the entire document.

The papal handle has not yet been disclosed but it is widely expected to be @BenedictusPPXVI, his name and title in Latin.

The pope has given a qualified blessing to social networking.

In a document issued last year, he said the possibilities of new media and social networks offered “a great opportunity”, but warned of the risks of depersonalisation, alienation, self-indulgence, and the dangers of having more virtual friends than real ones.

In 2009, a new Vatican website, www.pope2you.net, went live, offering an application called “The pope meets you on Facebook”, and another allowing the faithful to see the pontiff’s speeches and messages on their iPhones or iPods.

The Vatican famously got egg on its face in 2009 when it was forced to admit that, if it had surfed the web more, it might have known that a traditionalist bishop whose excommunication was lifted had for years been a Holocaust denier.

(Reporting By Philip Pullella; editing by Mike Collett-White)

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Italy lifts ban on Novartis flu vaccine

ROME (Reuters) – Italy lifted a ban on Novartis‘s flu vaccines on Friday after accepting the drugmaker had shown they posed no risk to safety.

The company said it hoped to quickly resume regular supplies around the European Union.

Italy banned the sale of anti-influenza vaccines produced by Novartis on October 24, pending tests for possible side effects after small particles were found in some of the injections.

The Italian pharmaceutical agency AIFA, a government body, said on Friday it had lifted the ban “following careful checks on the documentation produced by the company.”

The agency said its analyses had gone beyond its routine controls and had “confirmed the absence of defects” in the products, Agrippal and Fluad.

After Italy imposed its ban several other countries followed suit, including Switzerland, Austria, Germany, Spain, France, Canada and Singapore.

Canadian and Swiss authorities lifted their bans on October 31, and Singapore ended its suspension on November 2.

Novartis welcomed Italy’s decision and said it would “continue to work with other European Union countries to lift remaining precautionary measures and resume supply there as soon as possible.”

It said in a statement that for the 2012-2013 season more than one million doses had been administered “with no unexpected adverse events reported.”

(Reporting by Gavin Jones; Editing by James Mackenzie and David Cowell)

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Boehner: GOP has 'some work to do'

House Speaker John Boehner (Brendan Hoffman/Getty Images)

Reflecting on this week's election, in which Democratic President Barack Obama won re-election and Democrats made gains in Congress, House Speaker John Boehner said the GOP has "some work to do" in how it presents the party's ideas.

"It's clear that as a political party we've got some work to do," Boehner, an Ohio Republican, told reporters during a press conference on Capitol Hill on Friday. "I think the principles of our party are sound. We believe in individual responsibility, we believe in empowering our citizens. We believe in the American Dream. We want that dream for everyone. But how we talk about who we are as a party is clearly—clearly conversations are underway and will continue."

Congress faces a busy lame-duck session, as leaders from both chambers plan to work with the White House to reach a deal that will avoid automatic tax increases and spending cuts set to begin Jan. 1, 2013. Boehner said he's looking to Obama "to lead" and that he had a short, "cordial" conversation with the president earlier this week about ways to avoid the so-called fiscal cliff.

"I think we both understand that trying to find a way to avert the fiscal cliff is important for this country," Boehner said. "And I'm hopeful that productive conversations can begin soon so we can forge an agreement that can pass the Congress."

Boehner reiterated his opposition to raising taxes as part of that deal, even on high-income earners, and says he sees the negotiations as a way to overhaul the tax code and the way the federal government pays for entitlement programs like Social Security and Medicare.

The president, who will deliver a statement about the negotiations on Friday afternoon, has said that he remains committed to increasing taxes on the wealthy as part of his plan.

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Obama to call for deal to avert 'fiscal cliff'

President Obama will today call upon Congress to work with him on preserving the lower tax rates first pushed by President Bush for those Americans who earn under $200,000 a year, but he will state his belief that voters were clear in re-electing him that they support a "balanced approach" to deficit reduction - meaning that the lower tax rates for higher wage earners should expire.

The president, aides tell ABC News, will argue that the tax cuts for the middle class are something everyone agrees on, so there's no reason for them to be linked to tax cuts for wealthier Americans, about which there's more disagreement. This will be the president "setting the table" for negotiations with Congress, one White House official told ABC News, just as House Speaker John Boehner, R-Ohio, did yesterday when he expressed his determination to stop any de facto tax increase on higher wage earners.

A report issued yesterday by the non-partisan Congressional Budget Office warned about the consequences to the U.S. economy if no deal was struck and the Bush tax cuts expired in addition to all the other issues related to the so-called "fiscal cliff" - including the expiration of a payroll tax cut, indexing the alternative minimum tax for inflation, continuing emergency unemployment benefits, and spending cuts forced on the budget because of the failure of the poorly-titled "Super-Committee" to come up with $1.2 trillion in deficit reduction.

Get More News at ABC Politics and a Different Spin at OTUS News

The CBO predicted that should no deal be struck, "real (inflation-adjusted) gross domestic product (GDP) will drop by 0.5 percent in 2013? causing "employment to decline and the unemployment rate to rise to 9.1 percent in the fourth quarter of 2013."

The president will note that the CBO report states that most of the impact of the tax cuts relates to those wage-earners who make less than $200,000 a year. Extending all the Bush-initiated lower rates would boost GDP by 1.4% and help create 1.8 million jobs, the CBO report states, while allowing their expiration for those higher wage earners while maintaining the lower rates for those making $200,000 a year and less would boost GDP by 1.3% and generate 1.6 million jobs. The .1% in GDP growth and 200,000-job difference is already being described by progressive pundits as "minimal."

White House officials insist that they're confident that a deal will be struck. One top Obama adviser, however, told ABC News that if the House GOP refuses to cut a deal with the president that includes some tax increases on the wealthy, the tax cuts will expire. One scenario the official discussed included the president barn-storming the country, telling the public that Democrats will put forward a bill to restore middle class tax cuts as soon as Congress convenes, and calling on them to pressure Republican congressional leaders to stop holding those tax cuts hostage in exchange for tax cuts for wealthier Americans.

-Jake Tapper

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‘NBA 2K13′ tops video games titles in October

NEW YORK (AP) — U.S. retail sales of new video game hardware, software and accessories fell 25 percent in October, marking the 11th straight month of declining sales for physical game products, according to a report from NPD Group.

Many gamers are waiting for big holiday releases such as Activision‘s “Call of Duty: Black Ops II.”

NPD said sales fell to $ 755.5 million from $ 1 billion a year earlier. Sales of video games themselves, excluding PC titles, fell 25 percent to $ 432.6 million. Sales of hardware such as Microsoft‘s Xbox 360 fell 37 percent to $ 187.3 million. Sales of accessories, meanwhile, grew 5 percent to $ 135.6 million.

Thursday’s study from NPD Group tracks sales of new physical products — about 50 percent of the total spending. Excluded are sales of used games and rentals as well as digital and social-network spending.

NPD also listed the top-selling games in October:

1. “NBA 2K13,” Take-Two Interactive Software Inc.

2. “Resident Evil 6,” Capcom USA

3. “Pokemon Black Version 2,” Nintendo Co.

4. “Dishonored,” Bethesda Softworks

5. “Pokemon White Version 2,” Nintendo Co.

6. “Madden NFL 13,” Electronic Arts Inc.

7. “FIFA Soccer 13,” Electronic Arts Inc.

8. “Medal of Honor: Warfighter,” Electronic Arts Inc.

9. “Borderlands 2,” Take-Two Interactive Software Inc.

10. “Skylander Giants,” Activision Blizzard Inc.

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Tiny Tick May Be Spreading Vegetarianism

A tiny tick might be to blame for a rash of meat allergies in central and southern regions of the U.S.

A bite from the lone star tick, so-called for the white spot on its back, looks innocent enough. But researchers say saliva that sneaks into the wound might trigger a reaction to meat agonizing enough to convert lifelong carnivores into wary vegetarians.

“People will eat beef and then anywhere from three to six hours later start having a reaction; anything from hives to full-blown anaphylactic shock,” said Dr. Scott Commins, assistant professor of medicine at the University of Virginia in Charlottesville. “Most people want to avoid having the reaction, so they try to stay away from the food that triggers it.”

Cases of the bizarre allergy are cropping up in areas ripe with lone star ticks, according to research presented today at the American College of Allergy, Asthma and Immunology annual meeting in Anaheim, Calif. But whether the bugs cause meat allergies remains unclear.

“It’s hard to prove,” said Commins. “We’re still searching for the mechanism.”

Allergies are immune reactions to foreign substances, from pet hair to peanuts. As antibodies attack the substance that caused the reaction, they trigger the release of histamine, a chemical that causes hives and, in severe cases, life-threatening anaphylaxis.

Commins said blood levels of antibodies for alpha-gal, a sugar found in beef, lamb and pork, rise after a single bite from the lone star tick. He said he hopes experiments that combine tiny samples of tick saliva with the invisible antibodies will prove the two are directly connected.

“It’s complicated, no doubt,” said Commins. “But we think it’s something in the saliva.”

The long lag between exposure to meat and the allergic reaction complicates things even more.

“Most food allergies occur very quickly,” said Dr. Stanley Fineman, president of the American College of Allergy, Asthma and Immunology. “It’s also a bit unusual to see adults develop a food allergy.”

But the tick bite theory could help explain the sudden onset of some meat allergies, Fineman added.

Other Common food allergens include peanuts, shellfish, milk, eggs, soy and wheat. And most food allergy sufferers are glad to discover the source of their misery, even if it means upheaval for their diets.

“Avoidance is the best way to handle any food allergy,” he said.

But meat allergies are hard for some brawny barbecuers to swallow.

“Some people are totally destroyed,” said Commins. “Others say, ‘Maybe I’m better off without it.’”

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Assad says will live and die in Syria

DOHA (Reuters) – President Bashar al-Assad said he would “live and die” in Syria and warned that any Western invasion to topple him would have catastrophic consequences for the Middle East and beyond.

Assad’s defiant remarks coincided with a landmark meeting in Qatar on Thursday of Syria’s fractious opposition to hammer out an agreement on a new umbrella body uniting rebel groups inside and outside Syria, amid growing international pressure to put their house in order and prepare for a post-Assad transition.

The Syrian leader, battling a 19-month old uprising against his rule, appeared to reject an idea floated by British Prime Minister David Cameron on Tuesday that a safe exit and foreign exile for the London-educated Assad could end the civil war.

“I am not a puppet. I was not made by the West to go to the West or to any other country,” he told Russia Today television in an interview to be broadcast on Friday. “I am Syrian; I was made in Syria. I have to live in Syria and die in Syria.”

Russia Today’s web site, which published a transcript of the interview conducted in English, showed footage of Assad speaking to journalists and walking down stairs outside a white villa. It was not clear when he had made his comments.

The United States and its allies want the Syrian leader out, but have held back from arming his opponents or enforcing a no-fly zone, let alone invading. Russia has stood by Assad.

The president said he doubted the West would risk the global cost of intervening in Syria, whose conflict has already added to instability in the Middle East and killed some 38,000 people.

“I think that the price of this invasion, if it happened, is going to be bigger than the whole world can afford … It will have a domino effect that will affect the world from the Atlantic to the Pacific,” the 47-year-old president said.

“I do not think the West is going in this direction, but if they do so, nobody can tell what is next.”

QATAR, TURKEY CHIDE OPPOSITION

Backed by Washington, the Doha talks underline Qatar’s central role in the effort to end Assad‘s rule as the Gulf state, which funded the Libyan revolt to oust Muammar Gaddafi, tries to position itself as a player in a post-Assad Syria.

Qatari Prime Minister Hamad bin Jassim Al Thani urged the Syrian opposition to set its personal disputes aside and unite, according to a source inside the closed-door session.

“Come on, get a move on in order to win recognition from the international community,” the source quoted him as saying.

Turkish Foreign Minister Ahmed Davutoglu delivered a similar message, saying, according to the source: “We want one spokesman not many. We need efficient counterparts, it is time to unite.”

An official text of a speech by Qatari Foreign Minister Khalid Mohamed al-Attiyah showed he told the gathering: “The Syrian people awaits unity from you, not divisions … Your agreement today will prove to the international community that there is a unity … and this will reflect positively in the international community’s stance towards your fair cause.”

Across Syria, more than 90 people were killed in fighting on Thursday, the Syrian Observatory for Human Rights said.

In Turkey’s Hatay border province, two civilians, a woman and a young man, were wounded by stray bullets fired from Syria, according to a Turkish official. Turkish forces increased their presence along the frontier, where officials have said they might seek NATO deployment of ground to air missiles.

Syria poses one of the toughest foreign policy challenges for U.S. President Barack Obama as he starts his second term.

International rivalries have complicated mediation efforts. Russia and China have vetoed three Western-backed U.N. Security Council resolutions that would have put Assad under pressure.

Syria’s conflict, pitting mostly Sunni Muslim rebels against forces dominated by Assad’s Alawite minority, whose origins lie in Shi’ite Islam, has fuelled sectarian tensions across the Middle East. Sunni Arab countries and Turkey favor the rebels, while Shi’ite Iran backs Assad, its main Arab ally.

“VICIOUS CIRCLE”

The main opposition body, the Syrian National Council (SNC), has been heavily criticized by Western and Arab backers of the revolt as ineffective, run by exiles out of touch with events in Syria, and under the sway of the Islamist Muslim Brotherhood.

British Foreign Minister William Hague said London would now talk to rebel groups inside Syria, after U.S. Secretary of State Hillary Clinton last week criticized the SNC and called for a new opposition body to include those “fighting and dying”.

But the plan for a body that could eventually be considered a government-in-waiting capable of winning foreign recognition and therefore more military backing ran into trouble almost as soon as it was proposed by SNC member Riyad Seif.

The meeting has so far been bogged down by arguments over the SNC representation and the number of seats the rival groups – which include Islamists, leftists and secularists – will have in a proposed assembly. Seif said he hoped for agreement on that on Thursday night, although the talks may continue into Friday.

Senior SNC member Burhan Ghalioun said the participants were moving towards consensus: “The atmosphere was positive. We all agree that we don’t want to walk away from this meeting in failure,” he told reporters.

Seif’s proposal is the first concerted attempt to merge opposition forces to help end the devastating conflict.

The initiative would also create a Supreme Military Council, a Judicial Committee and a transitional government-in-waiting of technocrats – along the lines of Libya’s Transitional National Council, which managed to galvanize international support for its successful battle to topple Gaddafi.

Michael Doran of the Brookings Institute in Washington told a forum in Doha it would not work for Syria. “It’s not a ridiculous idea, but it’s not going to succeed,” he said.

A diplomat on the sidelines of the talks said international divisions in the U.N. Security council did not help.

“It’s a vicious circle. They are asking the opposition to unite when they admit they are not themselves united,” he said.

(Writing by Tom Perry and Samia Nakhoul; Editing by Alistair Lyon, Alastair Macdonald and Philippa Fletcher)

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Mark Wahlberg to star in next ‘Transformers’ movie

LOS ANGELES (AP) — Mark Wahlberg, roll out.

“Transformers” director Michael Bay says the 41-year-old actor will star in the franchise’s fourth film.

Bay called Wahlberg the “perfect guy to re-invigorate the franchise and carry on the Transformers‘ legacy” in a post on his blog Thursday. He previously squashed rumors that Wahlberg was joining the film franchise about warring robots.

Bay worked with Wahlberg on his upcoming film, “Pain and Gain.”

“Transformers 4″ is scheduled to be released by Paramount Pictures on June 27, 2014.

Bay has said the next film will take a new direction in the series. The first three movies starred Shia LaBeouf and featured Peter Cullen as the voice of Autobot general Optimus Prime.

The third “Transformers” film, “Dark of the Moon,” was the second highest-grossing film of 2011.

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Ghana building collapse traps dozens, kills 1

ACCRA, Ghana (AP) — A five-story shopping center built earlier this year in a bustling suburb of Ghana‘s capital collapsed Wednesday, killing at least one person and leaving several dozen people trapped in the rubble, authorities and eyewitnesses said.

Rescue crews used cranes to try and remove debris from the top of the building amid fears that machinery sifting through the wreckage could injure trapped survivors. Crowds of bystanders gathered as rescuers sifted through cement and glass.

The fatality at the Melcom Shopping Center at Achimota, a suburb of Accra, was confirmed by Public Affairs Officer of the Ghana Fire Service Billy Anaglate. “We are still working to find out the fate of others who may be trapped under,” he said.

Other officials told The Associated Press that the death toll was likely to rise.

An AP reporter at the scene saw at least one man pulled from the debris, covered in dust and who was then whisked into an ambulance.

A Greater Accra Regional Public Affairs officer, deputy superintendent Freeman Tettey, confirmed that one person died and told the AP that 51 have been rescued and sent to hospitals around the capital.

“I was on my way to the shop when l saw it crumpling down,” Kojo Boadi, an eyewitness, said.

President John Mahama declared the scene a disaster zone and cut short his election campaign in the north of the country to be able to visit the site. The presidential election is scheduled for December.

The five-story store opened in February is part of the Melcom chain owned by Indian immigrant magnate, Bhagwan Khubchandani. His late father arrived in Ghana in 1929 as a 14-year-old to work as a store boy in the-then Gold Coast.

The store sells a variety of cheap, imported household goods and appliances that are popular with working-class Ghanaians.

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Exclusive: Google Ventures beefs up fund size to $300 million a year

SAN FRANCISCO (Reuters) - Google will increase the cash it allocates to its venture-capital arm to up to $300 million a year from $200 million, catapulting Google Ventures into the top echelon of corporate venture-capital funds.

Access to that sizeable checkbook means Google Ventures will be able to invest in more later-stage financing rounds, which tend to be in the tens of millions of dollars or more per investor.

It puts the firm on the same footing as more established corporate venture funds such as Intel's Intel Capital, which typically invests $300-$500 million a year.

"It puts a lot more wood behind the arrow if we need it," said Bill Maris, managing partner of Google Ventures.

Part of the rationale behind the increase is that Google Ventures is a relatively young firm, founded in 2009. Some of the companies it backed two or three years ago are now at later stages, potentially requiring larger cash infusions to grow further.

Google Ventures has taken an eclectic approach, investing in a broad spectrum of companies ranging from medicine to clean power to coupon companies.

Every year, it typically funds 40-50 "seed-stage" deals where it invests $250,000 or less in a company, and perhaps around 15 deals where it invests up to $10 million, Maris said. It aims to complete one or two deals annually in the $20-$50 million range, Maris said.

LACKING SUPERSTARS

Some of its investments include Nest, a smart-thermostat company; Foundation Medicine, which applies genomic analysis to cancer care; Relay Rides, a carsharing service; and smart-grid company Silver Spring Networks. Last year, its portfolio company HomeAway raised $216 million in an initial public offering.

Still, Google Ventures lacks superstar companies such as microblogging service Twitter or online bulletin-board company Pinterest. The firm's recent hiring of high-profile entrepreneur Kevin Rose as a partner could help attract higher-profile deals.

Soon it could have even more cash to play around with. "Larry has repeatedly asked me: 'What do you think you could do with a billion a year?'" said Maris, referring to Google chief executive Larry Page.

(Editing by Muralikumar Anantharaman)

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UK PM warns of witch-hunt against gays in pedophile scandal

LONDON (Reuters) – British Prime Minister David Cameron warned on Thursday that speculation about the identity of an unidentified member of his ruling Conservative party accused of sexually abusing children could turn into a witch-hunt against gay people.

Cameron, who leads a troubled two-party coalition, ordered an investigation this week after a victim of child sexual abuse in Wales said a prominent Conservative political figure had abused him during the 1970s.

The claims, which follow the unmasking of late BBC star presenter Jimmy Savile as one of Britain’s most prolific sex offenders, have stoked concern that a powerful pedophile ring may have operated in Britain in the 1970s and 1980s.

“I have heard all sorts of names bandied around and what then tends to happen is of course that everyone then sits around and speculates about people, some of whom are alive, some of whom are dead,” Cameron said during an ITV television interview.

“It is very important that anyone who has got any information about any pedophile no matter how high up in the country go to the police,” he said.

Britain’s interior minister warned lawmakers this week that if they named suspected child abusers in parliament they risked jeopardizing future trials.

MPs benefit from “parliamentary privilege” – meaning they can speak inside parliament freely without fear of legal action on a host of legally sensitive issues that might otherwise attract lawsuits.

Reports of child abuse have provoked fevered speculation on the Internet about the identity of the Conservative figure from the era of Margaret Thatcher, prime minister from 1979 to 1990.

When the ITV interviewer passed Cameron a piece of paper with the names of people identified on the Internet as being alleged child abusers, Cameron said:

“There is a danger if we are not careful that this could turn into a sort of witch-hunt particularly against people who are gay.”

“I am worried about the sort of thing you are doing right now – giving me a list of names you have taken off the Internet,” Cameron said.

The BBC aired a program last week in which Steven Messham, one of hundreds of victims of sexual abuse at children’s care homes in Wales over two decades, said he had been sexually abused by a prominent Conservative political figure.

However, the BBC reporter said he could not name the figure because there was “simply not enough evidence to name names”.

(Reporting by Guy Faulconbridge; Editing by Andrew Osborn)

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FDA reviewing Merck’s experimental insomnia drug

WHITEHOUSE STATION, N.J. (AP) — Drugmaker Merck & Co. says the Food and Drug Administration is reviewing its experimental insomnia medication, suvorexant (SOO’vor-eks-ant).

The drug minimizes the morning grogginess common with many sleep aids. It could become a big seller for the Whitehouse Station, N.J., company.

If approved, it would be the first in a new class of medicines for patients with trouble falling or staying asleep. It works by temporarily blocking chemical messengers that keep people awake.

The FDA is doing a standard review, which usually takes 10 months. If approved, suvorexant would be a controlled substance like all hypnotic sleep drugs. They require additional government reviews taking four months or longer.

In studies, suvorexant’s most common side effects were tiredness and headache.

Merck also plans to seek approval for suvorexant in other countries.

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Giffords' husband faces shooter in court

TUCSON, Ariz. (AP) — Gabrielle Giffords came face to face Thursday with the man who tried to kill her last year, but chose not to speak.

Her astronaut husband, Mark Kelly, did all the talking for her, as the couple told Jared Lee Loughner how the 24-year-old's deadly rampage at the former congresswoman's political meeting had upended her life.

"Her life has been forever changed. Plans she had for our family and her career have been immeasurably altered," Kelly said at Loughner's sentencing. "Every day is a continuous stuggle to do those things she once was so good at."

Loughner showed no emotion, and looked at the other victims. His mother sobbed nearby.

"Mr. Loughner, you may have put a bullet through her head but you haven't put a dent in her spirit and her commitment to make the world a better place," Kelly said.

Giffords kissed Kelly when he was done. He grabbed her hand and they walked away, with her limping.

Earlier, Loughner told U.S. District Judge Larry Burns that he will not be speaking at the hearing where he is expected to be sentenced to life in prison.

Loughner pleaded guilty three months ago to 19 federal charges under an agreement that guarantees he will spend the rest of his life in prison without the possibility of parole. The deal calls for the dismissal of 30 other charges and a sentence of seven consecutive life terms, followed by 140 years in prison.

Both sides reached the deal after a judge declared that Loughner was able to understand the charges against him. After the shooting, he was diagnosed with schizophrenia and underwent forcible psychotropic drug treatments.

At the hearing, Loughner, who wore dress pants and a dark brown shirt with a tie, heard from his victims.

"We've been told about your demons, about the illness that skewed your thinking," said Susan Hileman, at times visibly shaking, to Loughner. "Your parents, your schools, your community, they all failed you.

"It's all true," Hileman said. "It's not enough."

"You pointed a weapon and shot me three times," she said, staring directly at Loughner. He looked back at her. "And now I walked out of this courtroom and into the rest of my life and I won't think of you again."

Some victims, including Giffords, welcomed the plea deal as a way to move on. It spared victims and their families from having to go through a potentially lengthy and traumatic trial and locks up the defendant for life.

Christina Pietz, the court-appointed psychologist who treated Loughner, had warned that although Loughner was competent to plead guilty, he remained severely mentally ill and his condition could deteriorate under the stress of a trial.

When Loughner first arrived at a Missouri prison facility for treatment, he was convinced Giffords was dead, even though he was shown a video of the shooting. He eventually realized she was alive after he was forcibly medicated.

It's unknown whether Pima County prosecutors, who have discretion on whether to seek the death penalty against Loughner, will file state charges against him. Stephanie Coronado, a spokeswoman for Pima County Attorney Barbara LaWall, said Wednesday that no decision had been made.

It's unclear where Loughner will be sent to serve his federal sentence. He could return to a prison medical facility like the one in Springfield, Mo., where he's been treated for more than a year. Or he could end up in a prison such as the federal lockup in Florence, Colo., that houses some of the country's most notorious criminals, including Oklahoma City bombing conspirator Terry Nichols and "Unabomber" Ted Kaczynski.

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New storm dumps snow, snuffs NE power

NEW YORK (AP) — The nor'easter that stymied recovery efforts from Superstorm Sandy pulled away from New York and New Jersey Thursday, leaving hundreds of thousands of new people in darkness after a blanket of thick, wet snow snapped storm-weakened trees and downed power lines.

From Brooklyn to storm-battered sections of the Jersey shore and Connecticut, about 750,000 customers — more than 200,000 from the new storm — in the region were without power in temperatures near freezing, some living for days in the dark.

"We lost power last week, just got it back for a day or two, and now we lost it again," said John Monticello of Point Pleasant Beach, N.J. "Every day it's the same now: turn on the gas burner for heat. Instant coffee. Use the iPad to find out what's going on in the rest of the world."

But most were just grateful the new storm didn't bring a fresh round of devastation.

"For a home without power, it's great. It came through the storm just great," said Iliay Bardash, 61, a computer programmer on Staten Island without electricity since last week. "But things are not worse, and for that I am thankful."

Nearby, Vladimir Repnin emerged from his powerless home with a snow shovel in his hand, a cigarette in his mouth and a question from someone cut off from the outside world.

"Who won? Obama?" he asked.

He didn't like the answer.

"The Democrats ruined my business," he said, referring to his shuttered clothing manufacturing firm.

Unlike other holdouts who got by with generators or gas stoves, the 63-year-old from the Ukraine has been without power since Sandy brought eight feet of water through his door and his neighbor's deck into his yard. He tried to beat the cold Wednesday night by sleeping with his Yorkie Kuzya and cat Channel.

"I had the dog right here," he said, pointing to his left side, "and the cat on my chest. It was still too cold, but I cannot leave my house."

Throughout Staten Island's beach area, the storm had blanketed growing piles of debris with several inches of snow. By mid-morning, it was starting to melt, filling the streets with filthy sludge.

Roads in New Jersey and New York City were clear for the morning commute, and rail lines into New York were running smoothly so far, despite snow still coming down heavily in some areas.

The nor'easter, as promised, brought gusting winds, rain and snow, but not the flooding that was anticipated.

"The good news, thank goodness, is except for maybe 2 inches of snow, there were no other problems," said Randi Savron, 51, a schoolteacher who lives in the Rockaways, one of the areas that flooded badly last week. The idyllic beachfront boardwalk was loosed from pilings and ended up outside her apartment building door.

She said it seemed like work would continue.

But additional outages could stall recovery efforts, even though utility companies had prepared, adding extra crews ahead of the nor'easter.

In New Jersey, there were about 400,000 power outages early Thursday; 150,000 of those were new. In New York City and Westchester, more than 70,000 customers were without power after the storm knocked out an additional 55,000 customers.

For Consolidated Edison, the extra outages were dealt with swiftly, so there were only about 3,000 additional customers without power from the total Wednesday of 67,000.

"I think we're going to be able to power through. Our objective was to get power restored to everyone by the weekend and we're still working with that goal," said Alfonso Quiroz, a spokesman for the utility.

On Long Island, an area badly battered, there were 125,000 new outages, but about 80,000 were restored, making a total of about 300,000 customers without power. Long Island Power Authority spokesman Mark Gross said the utility was assessing new damage while working to restore outages.

Paul Farash of West Babylon, N.Y. said he got power back after three days and didn't lose it again.

"Whatever I experienced was minimal compared to a whole lot of other people," he said. "I've seen some things. I've heard about some things. and I know some things. And I'm counting my blessings. I'll survive."

Anthony Gragnano, who lives in Lindenhurst, worried the new storm would further stall getting power returned to his flooded family home.

"It's just colder now," he said. "We still don't have heat or power, but aside from a little snow, we're good."

Under ordinary circumstances, a storm of this sort wouldn't be a big deal. But large swaths of the landscape were still an open wound, with the electrical system highly fragile and many of Sandy's victims still mucking out their homes and cars and shivering in the deepening cold. As the storm picked up in intensity Wednesday evening, lights started flickering off again.

Residents from Connecticut to Rhode Island saw 3 to 6 inches of snow on Wednesday. Worcester, Mass., had 8 inches of snow, and Freehold, N.J., had just over a foot overnight. Some parts of Connecticut got a foot or more.

There was good weather news: temperatures over the next few days will be in the 50s in southern New England, said meteorologist Frank Nocera, and on Sunday it could edge into the 60s.

Ahead of the storm, public works crews in New Jersey built up dunes to protect the stripped and battered coast, and new evacuations were ordered in a number of communities already emptied by Sandy. New shelters opened.

All construction in New York City was halted — a precaution that needed no explanation after a crane collapsed last week in Sandy's high winds and dangled menacingly over the streets of Manhattan. Parks were closed because of the danger of falling trees.

Airlines canceled at least 1,300 U.S. flights in and out of the New York metropolitan area, causing a new round of disruptions that rippled across the country.

Sandy killed more than 100 people in 10 states, with most of the victims in New York and New Jersey.

___

Contributing to this report were Associated Press writers Kiley Armstrong, Jonathan Fahey, Tom Hays, David B. Caruso, Meghan Barr, Jennifer Peltz and Deepti Hajela in New York; Jim Fitzgerald in White Plains, N.Y.; and Angela Delli Santi and Wayne Perry in Harvey Cedars, N.J. Eltman reported from Garden City, N.Y.

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Exclusive: Google Ventures beefs up fund size to $300 million a year

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